publikacije

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2016

  1. Ruan Y, Rezelj S, Bedina Zavec A, Anderluh G, Scheuring S (2016) Listeriolysin O Membrane Damaging Activity Involves Arc Formation and Lineaction -- Implication for Listeria monocytogenes Escape from Phagocytic Vacuole. PLoS Pathog 12: e1005597.
  2. Podobnik M, Savory P, Rojko N, Kisovec M, Wood N, Hambley R, Pugh J, Wallace EJ, McNeill L, Bruce M, Liko I, Allison TM, Mehmood S, Yilmaz N, Kobayashi T, Gilbert RJ, Robinson CV, Jayasinghe L, Anderluh G (2016) Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly. Nat Commun 7: 11598.
  3. Obradović D, Gašperšič R, Caserman S, Leonardi A, Jamnik M, Podlesek Z, Seme K, Anderluh G, Križaj I, Maček P, Butala M (2016) A Cytolethal Distending Toxin Variant from Aggregatibacter actinomycetemcomitans with an Aberrant CdtB That Lacks the Conserved Catalytic Histidine 160. PLoS One 11: e0159231.
  4. Makino A, Abe M, Ishitsuka R, Murate M, Kishimoto T, Sakai S, Hullin-Matsuda F, Shimada Y, Inaba T, Miyatake H, Tanaka H, Kurahashi A, Pack CG, Kasai RS, Kubo S, Schieber NL, Dohmae N, Tochio N, Hagiwara K, Sasaki Y, Aida Y, Fujimori F, Kigawa T, Nishibori K, Parton RG, Kusumi A, Sako Y, Anderluh G, Yamashita M, Kobayashi T, Greimel P, Kobayashi T (2016) A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release and in Niemann-Pick type C. FASEB J, in press.
  5. Zadravec P, Marečková L, Petroková H, Hodnik V, Perišić Nanut M, Anderluh G, Štrukelj B, Malý P, Berlec A (2016) Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit. PLoS One 11: e0162625.
  6. Podobnik M, Kraševec N, Bedina Zavec A, Naneh O, Flašker A, Caserman S, Hodnik V, Anderluh G (2016) How to Study Protein-protein Interactions. Acta Chim Slov 63: 424-439.
  7. Heggelund JE, Burschowsky D, Bjørnestad VA, Hodnik V, Anderluh G, Krengel U (2016) High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. PLoS Pathog 12(4): e1005567.
  8. Zavec AB, Kralj-Iglič V, Brinc M, Trček TF, Kuzman D, Schweiger A, Anderluh G (2016) Extracellular vesicles concentration is a promising and important parameter for industrial bioprocess monitoring. Biotechnol J : doi: 10.1002/biot.201500049.
  9. Wacklin HP, Bremec BB, Moulin M, Rojko N, Haertlein M, Forsyth T, Anderluh G, Norton RS (2016) Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation. Biochim Biophys Acta 1858(4): 640-652.
  10. Rojko N, Dalla Serra M, Maček P, Anderluh G (2016) Pore formation by actinoporins, cytolysins from sea anemones. Biochim Biophys Acta 1858(3): 446-456.
  11. Metkar SS, Pardo J, Anderluh G, Salvesen G, Trapani JA, Simon MM (2016) In memoriam: Prof Christopher J Froelich (1951-2015). Cell Death Differ 23(1): 3-4.

2015

  1. Rojko N, Anderluh G (2015) How Lipid Membranes Affect Pore Forming Toxin Activity. Acc Chem Res 48(12): 3073-3079.
  2. Rojko N, Zanetti M, Anderluh G, Dalla Serra M (2015) Properties of Pores Formed by Cholesterol-Dependent Cytolysins and Actinoporins. In: Electrophysiology of Unconventional Channels and Pores (Delcour AH, ed.). Springer, Heidelberg, 267-286.
  3. Naneh O, Zavec AB, Pahovnik D, Žagar E, Gilbert RJ, Križaj I, Anderluh G (2015) An optimized protocol for expression and purification of murine perforin in insect cells. J Immunol Methods 426: 19-28.
  4. Fornelos N, Butala M, Hodnik V, Anderluh G, Bamford JK, Salas M (2015) Bacteriophage GIL01 gp7 interacts with host LexA repressor to enhance DNA binding and inhibit RecA-mediated auto-cleavage. Nucleic Acids Res 43(15): 7315-7329.
  5. Cajnko MM, Marušić M, Kisovec M, Rojko N, Benčina M, Caserman S, Anderluh G (2015) Listeriolysin O Affects the Permeability of Caco-2 Monolayer in a Pore-Dependent and Ca2+-Independent Manner. PLoS One 10(6): e0130471.
  6. Miklavič Š, Kogovšek P, Hodnik V, Korošec J, Kladnik A, Anderluh G, Gutierrez-Aguirre I, Maček P, Butala M (2015) The Pseudomonas aeruginosa RhlR-controlled aegerolysin RahU is a low-affinity rhamnolipid-binding protein. FEMS Microbiol Lett 362(10): doi: 10.1093/femsle/fnv069.
  7. Weber DK, Yao S, Rojko N, Anderluh G, Lybrand TP, Downton MT, Wagner J, Separovic F (2015) Characterization of the Lipid-Binding Site of Equinatoxin II by NMR and Molecular Dynamics Simulation. Biophys J 108(8): 1987-1996.
  8. Podobnik M, Marchioretto M, Zanetti M, Bavdek A, Kisovec M, Cajnko MM, Lunelli L, Dalla Serra M, Anderluh G (2015) Plasticity of lysteriolysin O pores and its regulation by pH and unique histidine. Sci Rep 5: 9623. Erratum in: Sci Rep. 2015;5:15690.
  9. Novak M, Kraševec N, Skočaj M, Maček P, Anderluh G, Sepčić K (2015) Fungal aegerolysin-like proteins: distribution, activities, and applications. Appl Microbiol Biotechnol 99(2): 601-610.
  10. Makino A, Abe M, Murate M, Inaba T, Yilmaz N, Hullin-Matsuda F, Kishimoto T, Schieber NL, Taguchi T, Arai H, Anderluh G, Parton RG, Kobayashi T (2015) Visualization of the heterogeneous membrane distribution of sphingomyelin associated with cytokinesis, cell polarity, and sphingolipidosis. FASEB J 29(2): 477-493.
  11. Metkar SS, Marchioretto M, Antonini V, Lunelli L, Wang B, Gilbert RJ, Anderluh G, Roth R, Pooga M, Pardo J, Heuser JE, Serra MD, Froelich CJ (2015) Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes. Cell Death Differ 22(1): 74-85.

2014

  1. Gilbert RJC, Dalla Serra M, Froelich CJ, Wallace MI, Anderluh G (2014) Membrane pore formation at protein–lipid interfaces. Trends Biochem Sci 39(11): 510-516.
  2. Anderluh G, Kisovec M, Kraševec N, Gilbert RJ (2014) Distribution of MACPF/CDC proteins. In: MACPF/CDC Proteins - Agents of Defence, Attack and Invasion (Anderluh G, Gilbert RJ, eds.). Springer, 119-144.
  3. Cajnko MM, Mikelj M, Turk T, Podobnik M, Anderluh G (2014) Membrane interactions and cellular effects of MACPF/CDC proteins. In: MACPF/CDC Proteins - Agents of Defence, Attack and Invasion (Anderluh G, Gilbert RJ, eds.). Springer, 119-144.
  4. Kostan J, Salzer U, Orlova A, Törö I, Hodnik V, Senju Y, Zou J, Schreiner C, Steiner J, Meriläinen J, Nikki M, Virtanen I, Carugo O, Rappsilber J, Lappalainen P, Lehto VP, Anderluh G, Egelman EH, Djinović-Carugo K (2014) Direct interaction of actin filaments with F-BAR protein pacsin2. EMBO Rep 15(11): 1154-1162.
  5. Baker MA, Rojko N, Cronin B, Anderluh G, Wallace MI (2014) Photobleaching reveals heterogeneous stoichiometry for equinatoxin II oligomers. ChemBioChem 15(14): 2139-2145.
  6. Walter BM, Rupnik M, Hodnik V, Anderluh G, Dupuy B, Paulič N, Žgur-Bertok D, Butala M (2014) The LexA regulated genes of the Clostridium difficile. BMC Microbiol 14: 88.
  7. Novak M, Sepčić K, Kraševec N, Križaj I, Maček P, Anderluh G, Guella G, Mancini I (2014) Targeted lipid analysis of haemolytic mycelial extracts of Aspergillus niger. Molecules 19(7): 9051-9069.
  8. Rojko N, Cronin B, Danial JS, Baker MA, Anderluh G, Wallace MI (2014) Imaging the lipid-phase-dependent pore formation of equinatoxin II in droplet interface bilayers. Biophys J 106(8): 1630-1637.
  9. Skočaj M, Resnik N, Grundner M, Ota K, Rojko N, Hodnik V, Anderluh G, Sobota A, Maček P, Veranič P, Sepčić K (2014) Tracking cholesterol/sphingomyelin-rich membrane domains with the ostreolysin A-mCherry protein. PLoS One 9(3): e92783.
  10. Godinic-Mikulcic V, Jaric J, Greber BJ, Franke V, Hodnik V, Anderluh G, Ban N, Weygand-Durasevic I (2014) Archaeal aminoacyl-tRNA synthetases interact with the ribosome to recycle tRNAs. Nucleic Acids Res 42(8): 5191-5201.
  11. Gutiérrez-Aguirre I, Hodnik V, Glais L, Rupar M, Jacquot E, Anderluh G, Ravnikar M (2014) Surface plasmon resonance for monitoring the interaction of Potato virus Y with monoclonal antibodies. Anal Biochem 447: 74-81.

2013

  1. Marchioretto M, Podobnik M, Dalla Serra M, Anderluh G (2013) What planar lipid membranes tell us about the pore-forming activity of cholesterol-dependent cytolysins. Biophys Chem 182: 64-70.
  2. Švajger U, Brus B, Turk S, Sova M, Hodnik V, Anderluh G, Gobec S (2013) el toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screening. Eur J Med Chem 70: 393-399.
  3. Kovačič L, Paulič N, Leonardi A, Hodnik V, Anderluh G, Podlesek Z, Žgur-Bertok D, Križaj I, Butala M (2013) Structural insight into LexA-RecA* interaction. Nucleic Acids Res 41(21): 9901-9910.
  4. Rojko N, Kristan KČ, Viero G, Žerovnik E, Maček P, Dalla Serra M, Anderluh G (2013) Membrane damage by an α-helical pore-forming protein, Equinatoxin II, proceeds through a succession of ordered steps. J Biol Chem 288(33): 23704-23715.
  5. Ota K, Leonardi A, Mikelj M, Skočaj M, Wohlschlager T, Künzler M, Aebi M, Narat M, Križaj I, Anderluh G, Sepčić K, Maček P (2013) Membrane cholesterol and sphingomyelin, and ostreolysin A are obligatory for pore-formation by a MACPF/CDC-like pore-forming protein, pleurotolysin B. Biochimie 95(10): 1855-1864.
  6. Marušić M, Zupančič T, Hribar G, Komel R, Anderluh G, Caserman S (2013) The Caco-2 cell culture model enables sensitive detection of enhanced protein permeability in the presence of N-decyl-β-d-maltopyranoside. N Biotechnol 30(5): 507-515.
  7. Črnigoj M, Podlesek Z, Zorko M, Jerala R, Anderluh G, Ulrih NP (2013) Interactions of archaeal chromatin proteins alba1 and alba2 with nucleic acids. PLoS One 8(2): e58237.
  8. Mikelj M, Praper T, Demič R, Hodnik V, Turk T, Anderluh G (2013) Electroformation of giant unilamellar vesicles from erythrocyte membranes under low-salt conditions. Anal Biochem 435(2): 174-180.
  9. Laventie BJ, Potrich C, Atmanène C, Saleh M, Joubert O, Viero G, Bachmeyer C, Antonini V, Mancini I, Cianferani-Sanglier S, Keller D, Colin DA, Bourcier T, Anderluh G, van Dorsselaer A, Dalla Serra M, Prévost G (2013) p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions. Biochem J 450(3): 559-571.
  10. Skočaj M, Bakrač B, Križaj I, Maček P, Anderluh G, Sepčić K (2013) The sensing of membrane microdomains based on pore-forming toxins. Curr Med Chem 20(4): 491-501.
  11. Hodnik V, Anderluh G (2013) Surface plasmon resonance for measuring interactions of proteins with lipid membranes. In: Lipid-protein interactions: methods and protocols (Kleinschmidt J, ed.). Springer protocols, Humana Press, New York, 23-36.
  12. Gilbert RJ, Mikelj M, Dalla Serra M, Froelich CJ, Anderluh G (2013) Effects of MACPF/CDC proteins on lipid membranes. Cell Mol Life Sci 70: 2082-2093.

2012

  1. Milunović T, Kunstelj M, Fidler K, Anderluh G, Gaberc Porekar V (2012) Coupling purification and on-column PEGylation of tumor necrosis factor alpha analogue. Anal Biochem 430(2): 105-107.
  2. Škedelj V, Arsovska E, Tomašić T, Kroflič A, Hodnik V, Hrast M, Bešter-Rogač M, Anderluh G, Gobec S, Bostock J, Chopra I, O'Neill AJ, Randall C, Zega A (2012) 6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase. PLoS One 7(8): e39922.
  3. Mattiazzi M, Sun Y, Wolinski H, Bavdek A, Petan T, Anderluh G, Kohlwein SD, Drubin DG, Križaj I, Petrovič U (2012) A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis. PLoS One 7(7): e40931.
  4. De Colibus L, Sonnen AF, Morris KJ, Siebert CA, Abrusci P, Plitzko J, Hodnik V, Leippe M, Volpi E, Anderluh G, Gilbert RJ (2012) Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition. Structure 20(9): 1498-1507.
  5. Kahn SA, Biasoli D, Garcia C, Geraldo LH, Pontes B, Sobrinho M, Frauches AC, Romão L, Soletti RC, Assunção FD, Tovar-Moll F, de Souza JM, Lima FR, Anderluh G, Moura-Neto V (2012) Equinatoxin II Potentiates Temozolomide- And Etoposide-Induced Glioblastoma Cell Death. Curr Top Med Chem 12(19): 2082-2089.
  6. Anderluh G, Zerovnik E (2012) Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity. Front Mol Neurosci 5: 85.
  7. Yachi R, Uchida Y, Balakrishna BH, Anderluh G, Kobayashi T, Taguchi T, Arai H (2012) Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells. Genes Cells 17(8): 720-727.
  8. Brvar M, Perdih A, Renko M, Anderluh G, Turk D, Solmajer T (2012) Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors. J Med Chem 55(14): 6413-6426.
  9. Popovic M, Zlatev V, Hodnik V, Anderluh G, Felli IC, Pongor S, Pintar A (2012) Flexibility of the PDZ-binding motif in the micelle-bound form of Jagged-1 cytoplasmic tail. Biochim Biophys Acta 1818(7): 1706-1716.
  10. Brvar M, Perdih A, Hodnik V, Renko M, Anderluh G, Jerala R, Solmajer T (2012) In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B. Bioorg Med Chem 20(8): 2572-2580.
  11. Anko M, Majhenc J, Kogej K, Sillard R, Langel U, Anderluh G, Zorko M (2012) Influence of stearyl and trifluoromethylquinoline modifications of the cell penetrating peptide TP10 on its interaction with a lipid membrane. Biochim Biophys Acta 1818(3): 915-924.
  12. Bavdek A, Kostanjšek R, Antonini V, Lakey JH, Dalla Serra M, Gilbert RJ, Anderluh G (2012) pH dependence of listeriolysin O aggregation and pore-forming ability. FEBS J 279(1): 126-141.
  13. Conrado RJ, Wu GC, Boock JT, Xu H, Chen SY, Lebar T, Turnšek J, Tomšič N, Avbelj M, Gaber R, Koprivnjak T, Mori J, Glavnik V, Vovk I, Benčina M, Hodnik V, Anderluh G, Dueber JE, Jerala R, DeLisa MP (2012) DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res 40(4): 1879-1889.

2011

  1. Žager U, Lunder M, Hodnik V, Anderluh G, Čučnik S, Kveder T, Božič B (2011) Significance of K(L/V)WX(I/L/V)P epitope of the B2GPI in its (patho)physiologic function. eJIFCC 22(4): 7.
  2. Anderluh G, Sepčić K, Turk T, Maček P (2011) Cytolytic proteins from cnidarians - an overview. Acta Chim Slov 58(4): 724-729.
  3. Praper T, Sonnen A, Viero G, Kladnik A, Froelich CJ, Anderluh G, Dalla Serra M, Gilbert RJ (2011) Human perforin employs different avenues to damage membranes. J Biol Chem 286(4): 2946-2955.
  4. Praper T, Sonnen AF, Kladnik A, Andrighetti AO, Viero G, Morris KJ, Volpi E, Lunelli L, Dalla Serra M, Froelich CJ, Gilbert RJ, Anderluh G (2011) Perforin activity at membranes leads to invaginations and vesicle formation. Proc Natl Acad Sci U S A. 108(52): 21016-21021.
  5. Metkar SS, Wang B, Catalan E, Anderluh G, Gilbert RJ, Pardo J, Froelich CJ (2011) Perforin rapidly induces plasma membrane phospholipid flip-flop. PLoS One 6(9): e24286.
  6. García-Sáez AJ, Buschhorn SB, Keller H, Anderluh G, Simons K, Schwille P (2011) Oligomerization and pore formation by equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization. J Biol Chem 286(43): 37768-37777.
  7. Žager U, Irman Š, Lunder M, Škarabot M, Muševič I, Hodnik V, Anderluh G, Čučnik S, Kveder T, Rozman B, Božič B (2011) Immunochemical properties and pathological relevance of anti-β₂-glycoprotein I antibodies of different avidity. Int Immunol 23(8): 511-518.
  8. Butala M, Klose D, Hodnik V, Rems A, Podlesek Z, Klare JP, Anderluh G, Busby SJ, Steinhoff HJ, Zgur-Bertok D (2011) Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response. Nucleic Acids Res 39(15): 6546-6557.
  9. Popovic M, Bella J, Zlatev V, Hodnik V, Anderluh G, Barlow PN, Pintar A, Pongor S (2011) The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation. J Mol Recognit 24(2): 245-253.
  10. Žager U, Lunder M, Hodnik V, Anderluh G, Čučnik S, Kveder T, Božič B (2011) Significance of K(L/V)WX(I/L/V)P epitope of the B2GPI in its (patho)physiologic function. eJIFCC 22(4): .

2010

  1. Extraction of cholesterol from lipid membranes by methyl-beta-cyclodextrin: a surface plasmon resonance approach (2010) Bavdek A, Podlesnik Beseničar M, Maček P, Anderluh G. In: Cyclodextrins: chemistry and physics (Hu J, ed.). Transworld Research Network, Kerala, 47-59.
  2. Bakrač B, Anderluh G (2010) Molecular mechanism of sphingomyelin-specific membrane binding and pore formation by actinoporins. In: Proteins membrane binding and pore formation (Advances in experimental medicine and biology, Vol. 677) (Anderluh G, Lakey JH, eds.). Springer, New York, 106-115.
  3. Anderluh G, Lakey JH (2010) Proteins: membrane binding and pore formation. Preface. In: Proteins membrane binding and pore formation (Advances in experimental medicine and biology, Vol. 677) (Anderluh G, Lakey JH, eds.). Springer, New York, v-vi.
  4. Zemljic M, Rupnik M, Scarpa M, Anderluh G, Palù G, Castagliuolo I (2010) Repetitive domain of Clostridium difficile toxin B exhibits cytotoxic effects on human intestinal epithelial cells and decreases epithelial barrier function. Anaerobe 16(5): 527-532.
  5. Praper T, Besenicar MP, Istinic H, Podlesek Z, Metkar SS, Froelich CJ, Anderluh G (2010) Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH. Mol Immunol 47(15): 2492-2504.
  6. Soletti RC, Alves T, Vernal J, Terenzi H, Anderluh G, Borges HL, Gabilan NH, Moura-Neto V (2010) Inhibition of MAPK/ERK, PKC and CaMKII signaling blocks cytolysin-induced human glioma cell death. Anticancer Res 30(4): 1209-1215.
  7. Bakrac B, Kladnik A, Macek P, McHaffie G, Werner A, Lakey JH, Anderluh G (2010) A toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelin. J Biol Chem 285(29): 22186-22195.
  8. Kulma M, Hereć M, Grudziński W, Anderluh G, Gruszecki WI, Kwiatkowska K, Sobota A (2010) Sphingomyelin-rich domains are sites of lysenin oligomerization: implications for raft studies. Biochim Biophys Acta 1798(3): 471-481.
  9. Skerget K, Taler-Vercic A, Bavdek A, Hodnik V, Ceru S, Tusek-Znidaric M, Kumm T, Pitsi D, Pompe-Novak M, Palumaa P, Soriano S, Kopitar-Jerala N, Turk V, Anderluh G, Zerovnik E (2010) Interaction between oligomers of stefin B and amyloid-beta in vitro and in cells. J Biol Chem 285(5): 3201-3210.
  10. Drechsler A, Anderluh G, Norton RS, Separovic F (2010) Solid-state NMR study of membrane interactions of the pore-forming cytolysin, equinatoxin II. Biochim Biophys Acta 1798(2): 244-251.
  11. Lakey JH, Anderluh G (2010) Membrane disrupting proteins. In: Handbook of hydrocarbon and lipid microbiology (Timmis, KW, ed.). Springer, Berlin , 425-433.
  12. Podlesnik Beseničar M, Anderluh G (2010) Preparation of lipid membrane surfaces for molecular interaction studies by surface plasmon resonance biosensors. In: Surface plasmon resonance: methods and protocols, (Methods in molecular biology, vol. 627) (De Mol NJ, Fischer MJE, eds.). Springer, New York, 191-200.
  13. Hodnik V, Anderluh G (2010) Capture of intact liposomes in Biacore sensor chips for protein-membrane interaction studies. In: Surface plasmon resonance: methods and protocols, (Methods in molecular biology, vol. 627) (De Mol NJ, Fischer MJE, eds.). Springer, New York, 201-211.

2009

  1. Mirković B, Premzl A, Hodnik V, Doljak B, Jevnikar Z, Anderluh G, Kos J (2009) Regulation of cathepsin B activity by 2A2 monoclonal antibody. FEBS J 276(17): 4739-4751.
  2. Lorizate M, Brügger B, Akiyama H, Glass B, Müller B, Anderluh G, Wieland FT, Kräusslich HG (2009) Probing HIV-1 membrane liquid order by Laurdan staining reveals producer cell-dependent differences. J Biol Chem 284(33): 22238-22247.
  3. Ottmann C, Luberacki B, Küfner I, Koch W, Brunner F, Weyand M, Mattinen L, Pirhonen M, Anderluh G, Seitz HU, Nürnberger T, Oecking C (2009) A common toxin fold mediates microbial attack and plant defense. Proc Natl Acad Sci U S A. 106(25): 10359-10364.
  4. Tejuca M, Anderluh G, Dalla Serra M (2009) Sea anemone cytolysins as toxic components of immunotoxins. Toxicon 54(8): 1206-1214.
  5. Kristan KC, Viero G, Dalla Serra M, Macek P, Anderluh G (2009) Molecular mechanism of pore formation by actinoporins. Toxicon 54(8): 1125-1134.
  6. Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn J, Klein JS, Katsamba PS, Waddell MB, Scott M, Thompson J, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, Clabbers A, Wieckowski S, Murphy MM, Page P, Ryan TE, Duffner J, Ganguly T, Corbin J, Gautam S, Anderluh G, Bavdek A, Reichmann D, Yadav SP, Hommema E, Pol E, Drake A, Klakamp S, Chapman T, Kernaghan D, Miller K, Schuman J, Lindquist K, Herlihy K, Murphy MB, Bohnsack R, Andrien B, Brandani P, Terwey D, Millican R, Darling RJ, Wang L, Carter Q, Dotzlaf J, Lopez-Sagaseta J, Campbell I, Torreri P, Hoos S, England P, Liu Y, Abdiche Y, Malashock D, Pinkerton A, Wong M, Lafer E, Hinck C, Thompson K, Primo CD, Joyce A, Brooks J, Torta F, Bagge Hagel AB, Krarup J, Pass J, Ferreira M, Shikov S, Mikolajczyk M, Abe Y, Barbato G, Giannetti AM, Krishnamoorthy G, Beusink B, Satpaev D, Tsang T, Fang E, Partridge J, Brohawn S, Horn J, Pritsch O, Obal G, Nilapwar S, Busby B, Gutierrez-Sanchez G, Gupta RD, Canepa S, Witte K, Nikolovska-Coleska Z, Cho YH, D'Agata R, Schlick K, Calvert R, Munoz EM, Hernaiz MJ, Bravman T, Dines M, Yang MH, Puskas A, Boni E, Li J, Wear M, Grinberg A, Baardsnes J, Dolezal O, Gainey M, Anderson H, Peng J, Lewis M, Spies P, Trinh Q, Bibikov S, Raymond J, Yousef M, Chandrasekaran V, Feng Y, Emerick A, Mundodo S, Guimaraes R, McGirr K, Li YJ, Hughes H, Mantz H, Skrabana R, Witmer M, Ballard J, Martin L, Skladal P, Korza G, Laird-Offringa I, Lee CS, Khadir A, Podlaski F, Neuner P, Rothacker J, Rafique A, Dankbar N, Kainz P, Gedig E, Vuyisich M, Boozer C, Ly N, Toews M, Uren A, Kalyuzhniy O, Lewis K, Chomey E, Pak BJ, Myszka DG (2009) A global benchmark study using affinity-based biosensors. Anal Biochem 386(2): 194-216.
  7. Hodnik V, Anderluh G (2009) Toxin detection by surface plasmon resonance. Sensors (Basel) 9(3): 1339-1354.

2008

  1. Ceru S, Kokalj SJ, Rabzelj S, Skarabot M, Gutierrez-Aguirre I, Kopitar-Jerala N, Anderluh G, Turk D, Turk V, Zerovnik E (2008) Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B. Amyloid 15(3): 147-159.
  2. Anderluh G, Lakey JH (2008) Disparate proteins use similar architectures to damage membranes. Trends Biochem Sci 33(10): 482-490.
  3. Bakrac B, Gutiérrez-Aguirre I, Podlesek Z, Sonnen AF, Gilbert RJ, Macek P, Lakey JH, Anderluh G (2008) Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin. J Biol Chem 283(27): 18665-18677.
  4. Miles AJ, Drechsler A, Kristan K, Anderluh G, Norton RS, Wallace BA, Separovic F (2008) The effects of lipids on the structure of the eukaryotic cytolysin equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study. Biochim Biophys Acta 1778(10): 2091-2096.
  5. Besenicar MP, Metkar S, Wang B, Froelich CJ, Anderluh G (2008) Granzyme B translocates across the lipid membrane only in the presence of lytic agents. Biochem Biophys Res Comm 371(3): 391-394.
  6. Soletti RC, de Faria GP, Vernal J, Terenzi H, Anderluh G, Borges HL, Moura-Neto V, Gabilan NH (2008) Potentiation of anticancer-drug cytotoxicity by sea anemone pore-forming proteins in human glioblastoma cells. Anticancer Drugs 19(5): 517-525.
  7. Rabzelj S, Viero G, Gutiérrez-Aguirre I, Turk V, Dalla Serra M, Anderluh G, Zerovnik E (2008) Interaction with model membranes and pore formation by human stefin B: studying the native and prefibrillar states. FEBS J 275(10): 2455-2466.
  8. Schön P, García-Sáez AJ, Malovrh P, Bacia K, Anderluh G, Schwille P (2008) Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence. Biophys J 95(2): 691-698.
  9. Besenicar MP, Bavdek A, Kladnik A, Macek P, Anderluh G (2008) Kinetics of cholesterol extraction from lipid membranes by methyl-beta-cyclodextrin-a surface plasmon resonance approach. Biochim Biophys Acta 1778(1): 175-184.

2007

  1. Kristan K, Viero G, Macek P, Dalla Serra M, Anderluh G (2007) The equinatoxin N-terminus is transferred across planar lipid membranes and helps to stabilize the transmembrane pore. FEBS J 274(2): 539-550.
  2. Butala M, Hodoscek M, Anderluh G, Podlesek Z, Zgur-Bertok D (2007) Intradomain LexA rotation is a prerequisite for DNA binding specificity. FEBS Lett 581(25): 4816-4820.
  3. Bavdek A, Gekara NO, Priselac D, Gutiérrez Aguirre I, Darji A, Chakraborty T, Macek P, Lakey JH, Weiss S, Anderluh G (2007) Sterol and pH interdependence in the binding, oligomerization, and pore formation of Listeriolysin O. Biochemistry 46(14): 4425-4437.

2006

  1. Gutiérrez-Aguirre I, Trontelj P, Macek P, Lakey JH, Anderluh G (2006) Membrane binding of zebrafish actinoporin-like protein: AF domains, a novel superfamily of cell membrane binding domains. Biochem J 398(3): 381-392.
  2. Besenicar M, Macek P, Lakey JH, Anderluh G (2006) Surface plasmon resonance in protein-membrane interactions. Chem Phys Lipids 141(1-2): 169-178.
  3. Drechsler A, Potrich C, Sabo JK, Frisanco M, Guella G, Dalla Serra M, Anderluh G, Separovic F, Norton RS (2006) Structure and activity of the N-terminal region of the eukaryotic cytolysin equinatoxin II. Biochemistry 45(6): 1818-1828.

2005

  1. Petrovic U, Sribar J, Matis M, Anderluh G, Peter-Katalinić J, Krizaj I, Gubensek F (2005) Ammodytoxin, a secretory phospholipase A2, inhibits G2 cell-cycle arrest in the yeast Saccharomyces cerevisiae. Biochem J 391(2): 383-388.
  2. Anderluh G, Besenicar M, Kladnik A, Lakey JH, Macek P (2005) Properties of nonfused liposomes immobilized on an L1 Biacore chip and their permeabilization by a eukaryotic pore-forming toxin. Anal Biochem 344(1): 43-52.
  3. Anderluh G, Gutierrez-Aguirre I, Rabzelj S, Ceru S, Kopitar-Jerala N, Macek P, Turk V, Zerovnik E (2005) Interaction of human stefin B in the prefibrillar oligomeric form with membranes. Correlation with cellular toxicity. FEBS J 272(12): 3042-3051.
  4. Anderluh G, Gutierrez-Aguirre I, Sepčić K, Maček P (2005) Pore forming toxins as useful tools in studies of lipid membrane organization. Proceedings of the Indian National Science Academy. Part B, Biological sciences 71: 73-82.
  5. Berne S, Sepcić K, Anderluh G, Turk T, Macek P, Poklar Ulrih N (2005) Effect of pH on the pore forming activity and conformational stability of ostreolysin, a lipid raft-binding protein from the edible mushroom Pleurotus ostreatus. Biochemistry 44(33): 11137-11147.
  6. Gokce I, Woody RW, Anderluh G, Lakey JH (2005) Single peptide bonds exhibit poly(pro)II ("random coil") circular dichroism spectra. J Am Chem Soc 127(27): 9700-9701.
  7. Potrich C, Tomazzolli R, Dalla Serra M, Anderluh G, Malovrh P, Macek P, Menestrina G, Tejuca M (2005) Cytotoxic activity of a tumor protease-activated pore-forming toxin. Bioconjug Chem 16(2): 369-376.
  8. Sribar J, Anderluh G, Fox JW, Krizaj I (2005) Protein disulphide isomerase binds ammodytoxin strongly: possible implications for toxin trafficking. Biochem Biophys Res Commun 329(2): 733-737.
  9. Anderluh G, Lakey JH (2005) Lipid interactions of alpha-helical protein toxins. In: Protein-lipid interactions: from membrane domains to cellular networks (Tamm L, ed.). Wiley-VCH, Weinheim, 141-162.
  10. Anderluh G, Razpotnik A, Podlesek Z, Macek P, Separovic F, Norton RS (2005) Interaction of the eukaryotic pore-forming cytolysin equinatoxin II with model membranes: 19F NMR studies. J Mol Biol 347(1): 27-39.

2004

  1. Gutiérrez-Aguirre I, Barlic A, Podlesek Z, Macek P, Anderluh G, González-Mañas JM (2004) Membrane insertion of the N-terminal alpha-helix of equinatoxin II, a sea anemone cytolytic toxin. Biochem J 384(2): 421-428.
  2. Kristan K, Podlesek Z, Hojnik V, Gutiérrez-Aguirre I, Guncar G, Turk D, González-Mañas JM, Lakey JH, Macek P, Anderluh G (2004) Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich. J Biol Chem 279(45): 46509-46517.
  3. Ulrih NP, Anderluh G, Macek P, Chalikian TV (2004) Salt-induced oligomerization of partially folded intermediates of equinatoxin II. Biochemistry 43(29): 9536-9545.
  4. Anderluh G, Gökçe I, Lakey JH (2004) A natively unfolded toxin domain uses its receptor as a folding template. J Biol Chem 279(21): 22002-22009.

2003

  1. Anderluh G, Maček P (2003) Dissecting the actinoporin pore-forming mechanism. Structure 11(11): 1312-1313.
  2. Anderluh G, Dalla Serra M, Viero G, Guella G, Macek P, Menestrina G (2003) Pore formation by equinatoxin II, a eukaryotic protein toxin, occurs by induction of nonlamellar lipid structures. J Biol Chem 278(46): 45216-45223.
  3. Anderluh G, Macek P, Lakey JH (2003) Peeking into a secret world of pore-forming toxins: membrane binding processes studied by surface plasmon resonance. Toxicon 42(3): 225-228.
  4. Anderluh G, Hong Q, Boetzel R, MacDonald C, Moore GR, Virden R, Lakey JH (2003) Concerted folding and binding of a flexible colicin domain to its periplasmic receptor TolA. J Biol Chem 278(24): 21860-21868.
  5. Malovrh P, Viero G, Serra MD, Podlesek Z, Lakey JH, Macek P, Menestrina G, Anderluh G (2003) A novel mechanism of pore formation: membrane penetration by the N-terminal amphipathic region of equinatoxin. J Biol Chem 278(25): 22678-22685.
  6. Anderluh G, Maček P (2003) Actinoporins, pore-forming toxins of sea anemones (Actiniara). In: Pore-forming peptides and protein toxins (Cellular and molecular mechanisms of toxin action, v. 5) (Menestrina G, Dalla Serra M, eds.). Taylor & Francis, New York, London, 132-147.
  7. Bonev BB, Lam YH, Anderluh G, Watts A, Norton RS, Separovic F (2003) Effects of the eukaryotic pore-forming cytolysin Equinatoxin II on lipid membranes and the role of sphingomyelin. Biophys J 84(4): 2382-2392.
  8. Anderluh G, Gökçe I, Lakey JH (2003) Expression of proteins using the third domain of the Escherichia coli periplasmic-protein TolA as a fusion partner. Protein Expr Purif 28(1): 173-181.

2002

  1. Hong Q, Gutierrez-Aguirre I, Barlic A, Malovrh P, Kristan K, Podlesek Z, Macek P, Turk D, Gonzalez-Manas JM, Lakey JH, Anderluh G (2002) Two-step membrane binding by Equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix. J Biol Chem 277(44): 41916-41924.
  2. Hinds MG, Zhang W, Anderluh G, Hansen PE, Norton RS (2002) Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation. J Mol Biol 315(5): 1219-1229.
  3. Anderluh G, Maček P (2002) Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria). Toxicon 40(2): 111-124.

2001

  1. Anderluh G, Menestrina G (2001) Pore-forming proteins from sea anemones and the construction of immunotoxins for selective killing of harmful cells. In: Recent advances in marine biotechnology. Vol. 6, Bio-organic compounds: chemistry and biomedical applications (Fingerman M, Nagabhushanam R, et al.). Science Publishers Inc., Enfield, Plymouth, 131-148.
  2. Athanasiadis A, Anderluh G, Macek P, Turk D (2001) Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina. Structure 9(4): 341-346.
  3. Poklar N, Völker J, Anderluh G, Macek P, Chalikian TV (2001) Acid- and base-induced conformational transitions of equinatoxin II. Biophys Chem 90(2): 103-121.

2000

  1. Zhang W, Hinds MG, Anderluh G, Hanse PE, Norton RS (2000) Letter to the editor: Sequence-specific resonance assignments of the potent cytolysin equinatoxin II. J Biomol NMR 18(3): 281-282.
  2. Brecelj M, Pikelj F, Gubensek F, Anderluh G (2000) Polymerase chain reaction as a diagnostic tool for detecting Leishmania. Infection 28(2): 111-113.
  3. Anderluh G, Podlesek Z, Macek P (2000) A common motif in proparts of Cnidarian toxins and nematocyst collagens and its putative role. Biochim Biophys Acta 1476(2): 372-376.
  4. Malovrh P, Barlic A, Podlesek Z, MaCek P, Menestrina G, Anderluh G (2000) Structure-function studies of tryptophan mutants of equinatoxin II, a sea anemone pore-forming protein. Biochem J 346(1): 223-232.
  5. Anderluh G, Barlic A, Potrich C, Macek P, Menestrina G (2000) Lysine 77 is a key residue in aggregation of equinatoxin II, a pore-forming toxin from sea anemone Actinia equina. J Membr Biol 173(1): 47-55.

1999

  1. Anderluh G, Barlic A, Podlesek Z, Macek P, Pungercar J, Gubensek F, Zecchini ML, Serra MD, Menestrina G (1999) Cysteine-scanning mutagenesis of an eukaryotic pore-forming toxin from sea anemone: topology in lipid membranes. Eur J Biochem 263(1): 128-136.
  2. Anderluh G, Krizaj I, Strukelj B, Gubensek F, Macek P, Pungercar J (1999) Equinatoxins, pore-forming proteins from the sea anemone Actinia equina, belong to a multigene family. Toxicon 37(10): 1391-1401.
  3. Tejuca M, Anderluh G, Macek P, Marcet R, Torres D, Sarracent J, Alvarez C, Lanio ME, Dalla Serra M, Menestrina G (1999) Antiparasite activity of sea-anemone cytolysins on Giardia duodenalis and specific targeting with anti-Giardia antibodies. Int J Parasitol 29(3): 489-498.

1998

  1. Anderluh G, Barlic A, Krizaj I, Menestrina G, Gubenšek F, Maček P (1998) Avidin-FITC topological studies with three cysteine mutants of equinatoxin II, a sea anemone pore-forming protein. Biochem Biophys Res Commun 242(1): 187-190.

1997

  1. Pungercar J, Anderluh G, Macek P, Franc G, Strukelj B (1997) Sequence analysis of the cDNA encoding the precursor of equinatoxin V, a newly discovered hemolysin from the sea anemone Actinia equina. Biochim Biophys Acta 1341(1): 105-107.
  2. Anderluh G, Pungercar J, Krizaj I, Strukelj B, Gubensek F, Macek P (1997) N-terminal truncation mutagenesis of equinatoxin II, a pore-forming protein from the sea anemone Actinia equina. Protein Eng 10(7): 751-755.

1996

  1. Anderluh G, Pungercar J, Strukelj B, Macek P, Gubensek F (1996) Cloning, sequencing, and expression of equinatoxin II. Biochem Biophys Res Commun 220(2): 437-442.

1995

  1. Anderluh G, Pungerčar J, Štrukelj B, Maček P, Gubenšek F (1995) The coding region of the equinatoxin II gene lacks introns. Croatica Chemica Acta 68(3): 533-542.