Representative Publications

Praper T, Sonnen AF, Kladnik A, Andrighetti AO, Viero G, Morris KJ, Volpi E, Lunelli L, Dalla Serra M, Froelich CJ, Gilbert RJ, Anderluh G (2011) Perforin activity at membranes leads to invaginations and vesicle formation. Proc Natl Acad Sci U S A. 108(52): 21016-21021. [pdf] [PubMed]

Bavdek A, Kostanjšek R, Antonini V, Lakey JH, Dalla Serra M, Gilbert RJ, Anderluh G (2011) pH dependence of listeriolysin O aggregation and pore-forming ability. FEBS J 279(1): 126-141. [pdf] [PubMed]

Praper T, Sonnen A, Viero G, Kladnik A, Froelich CJ, Anderluh G, Dalla Serra M, Gilbert RJ (2011) Human perforin employs different avenues to damage membranes. J Biol Chem 286(4): 2946-2955.[pdf][PubMed]

Bakrac B, Kladnik A, Macek P, McHaffie G, Werner A, Lakey JH, Anderluh G (2010) A toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelin. J Biol Chem 285(29): 22186-22195.[pdf] [PubMed]

Kristan KC, Viero G, Dalla Serra M, Macek P, Anderluh G (2009) Molecular mechanism of pore formation by actinoporins. Toxicon 54(8): 1125-1134.[pdf] [PubMed]

Bakrac B, Gutiérrez-Aguirre I, Podlesek Z, Sonnen AF, Gilbert RJ, Macek P, Lakey JH, Anderluh G (2008) Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin. J Biol Chem 283(27): 18665-18677.[pdf] [PubMed]

Anderluh G, Lakey JH (2008) Disparate proteins use similar architectures to damage membranes Trends Biochem Sci 33(10): 482-490.[pdf] [PubMed]

Journal Cover

Our research was presented on the cover page of Biochemical Journal. In this issue we described novel sequences with similarity to actinoporins and proposed a novel superfamily of peripheral membrane-binding proteins, AF domains (Gutiérrez-Aguirre I, Trontelj P, Maček P, Lakey JH, Anderluh G (2006) Membrane binding of zebrafish actinoporin-like protein: AF domains, a novel superfamily of cell membrane binding domains. Biochemical Journal 398: 381-392).